The present study has tried to make a comparison between perceived Mood-States of Adolescents possessing A+, B+, AB+ and O+ Blood Group. For this data was collected on 200 respondents: 100 boys and 100 Girls equally divided into four categories on the basis of their Blood- Group (Boys=100, A+=25. B+=25, AB+=25 and O+=25, Girls=100, A+=25. B+=25, AB+=25 and O+=25). 8SQ constructed by Cattle and Currans (1989) was utilized to measure the perceived Mood-State of the respondents. The present study have revealed that 1. Anxiety and Guilt were reported more by the Adolescents who possessed A+ type of blood-group while Depression and Fatigue were found to report more among Type O+ respondents. 2. Boys were found to report more Anxiety, Fatigue and Arousal while girls were found to report more Guilt as compared to boys. No other significant results were found on other dimensions of Mood-States.