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Occupational poisoning by chloroacetyl chloride

Author: 
Dr. Mahesh Dave, Dr. Sushma N., Dr. Deepanshu, Dr. Shubangi Gupta, Dr. Kanishk Amera, Dr. Neha Jain
Subject Area: 
Health Sciences
Abstract: 

Introduction: Chloroacetyl chloride is chlorinated acyl chloride it is bifunctional compound thus making it useful building block chemical in many chemical reactions. It is corrosive to eye and skin on contact. Liquid or spray mist produces tissue damage particularly on mucous membrane of eyes, mouth, respiratory tract and can cause multi-organ dysfunction because of oxidative and hypoxic effect. Case report: 29 year old male patient presented to us with history of exposure to white colored smoke that formed after accidental spillage of Chloroacetyl chloride on floor containing water. He complained of redness and watering of eyes, vomiting and shortness of breath, as there is no specific antidote available he treated symptomatically and put on mechanical ventilation for respiratory distress for 3 days. After 5 days he made fully recovery and discharged from hospital. Conclusion: - As one of the few documented cases of chloroacetyl chloride exposure, this case report contributes to the limited literature and emphasizes the potential risks of chloroacetyl chloride exposure and the need for further research and increased awareness among healthcare professionals.

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