Medicinal plants are an important source in the development of therapeutic strategies. Dacryodes edulis (G. Don) HJ. Lam (Burseraceae), a plant used for its alicamentary, medicinal properties and potential food, is one of this therapeutic arsenal. Phytochemical studies have revealed the presence of various chemical components that justify the diversity of medicinal indications attributed to this plant. The fruits of D.edulis are rich in fats, vitamins, protein and antioxidants. D.edulis present also antimicrobial, larvicidal, immunostimulating, anti-inflammatory, antioxidant, and hypoglycemic potentiality. Psychopharmacological studies have demonstrated a psychotropic profile of antidepressants and anxiolytics of essential oil of the pulp of the fruit. This review providesdetails on chemical profile, medicinal potentials and pharmacological activities of this plant, that constitute a support for the development of new drugs.