Tannery effluents such as chrome and dye liquor are mostly responsible for water pollution. At present, there is growing interest in using low cost, commercially available adsorbent for the adsorption of contaminants. Activated cow bone adsorbent was prepared and characterized by infra-red (IR) spectroscopy and scanning electron microscopy (SEM). Different parameters of chrome and dye liquor such as BOD, COD, TDS, TSS and electrical conductivity were measured before and after adsorption with activated cow bone charcoal. From the experimental results, it reveals that BOD, COD, TSS, TDS and electrical conductivity (EC) of chrome and dye liquor were reduced significantly after adsorption with activated cow bone charcoal. Thus the activated cow bone charcoal may be used for treating the tannery effluents to mitigate environmental pollution.