Background and Objectives: Beta blockers, one of the prescribed classes of cardio vascular medications reduce morbidity and mortality in patients with cardiac disease. It is highly necessary for the clinical pharmacist to review and clinically check all prescriptions presented at the wards. This study aims to assess the prescribing pattern of beta blockers in Acute Coronary Syndrome in the study population. Methods: This is a prospective observational study conducted in 108 patients, diagnosed with Acute Coronary Syndrome. Each patient medication profile was reviewed and recorded in the customised data entry form and patient demographic details, prescribing drugs and adverse drug reactions were noted from patients case sheet and patients interview. Patients prescribed with beta blockers will be assessed at the baseline and also at the time of follow up after 2 months. Results and Discussion: 87% were prescribed with Metoprolol and 8.3% were with Bisoprolol and 4.3% were prescribed with Carvedilol . 4.6 % of the patients show brady arrhythmia as the most predominant adverse drug reaction. Conclusion: Most predominant beta blocker prescribed for Acute Coronary Syndrome patients was Metoprolol than Bisoprolol and Carvedilol. Metoprolol was found to have very fewer adverse drug reactions.