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A rare case of early migration of ozurdex pellet into anterior chamber

Author:

Aaradhana Reddy

Subject Area:

Health Sciences

Abstract:

A 65 year old male patient who was given dexamethasone intravitreal implant (DEX implant; Ozurdex, Allergan Inc.) 1 week ago presented to us with chief complaint of sudden decrease in vision since 3 days. On slit lamp examination corneal edema was noted and we found the ozurdex implant in anterior chamber.The DEX implant is a non-tethered biodegradable sustained release implant containing 0.7 mg dexamethasone in the Novadur (Allergan) solid polymer drug-delivery system. These implants can occasionally migrate into the anterior chamber, causing vision-threatening complications that involve permanent corneal decompensation. We would like to report this case of early migration of ozurdex pellet into anterior chamber and review the literature pertaining to the anterior chamber migration of implant.

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