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Role of target therapy and immunotherapy in a rare case of ca colon with left sided krukenbergs tumor and benign spindle cell tumor in left lung: A case report

Author: 
Shifan Khanday, Ghayoor Abdul Wahab, Kaltham Al Shaibah, RehamJasem and Baidaa Jasem
Subject Area: 
Health Sciences
Abstract: 

Context: We are presenting a rare case of carcinoma colon (grade 4) with metastasis to left ovary (Krukenbergs) and benign spindle cell tumor in left lung diagnosed in a 65-year-old female. A brief literature review is presented. Patient was treated with CAPOX (Capecitabine and Oxyplatin) and Immunotherapy (Cetuximab). Surgical removal of left ovary and apparently no signs of cancer after 6 months of treatment. Inference: This case report highlights the potential benefit of combination of Target therapy and immunotherapy in the treatment of Krukenberg tumor. Although further studies are needed, immunotherapy could be considered as a treatment option in patients with Krukenberg tumor who have exhausted standard chemotherapy options. As our knowledge we report first case of simultaneously rare varieties of colon cancer and benign spindle cell tumor of lung. In a patient with history of malignancy, a benign mass should be diagnosed correctly with PET, core needle and IHC.

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