CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Single centred prospective controlled study on nail fold capillaroscopy and correlation with nail microvessel density in psoriatic patients in central India

Author: 
Dr. Sonali Gupta, Dr. Poonam Singh, Dr. Garima Goel, Dr. Shreya, K., Dr. Dinesh P Asati and Dr. Kapil Baheti
Subject Area: 
Health Sciences
Abstract: 

Background: Psoriasis involves vasculature in the very early stages of the disease leading to impaired capillary permeability, decreased density of capillaries and loss of adhesion between endothelial cell and the matrix of papillary dermis. It is hypothesized that early endothelial dysfunction can be detected at the level of dermal capillary microvasculature. If these changes can be detected and quantified early they would help in the early diagnosis of psoriasis, course of the disease and response to the treatment. Methods: Single centred prospective controlled study was conducted on 100 patients with psoriasis attending the outpatient department of dermatology between March 2021 and August 2022. Inclusion criteria involved patients above 10 years of age and less than 80 years of age with moderate to severe psoriasis with or without psoriatic arthritis and PASI≥10 or BSA >10% and off systemic treatment for a minimum of 4 weeks. Controls were selected from individuals who had never been diagnosed with psoriasis. Data recorded was statistically analysed by using Chi-square (for ordinal data) or by t-test (for continuous data) and by non-parametric test. A p value<0.05 was considered as statistically significant for this purpose. Results: The mean age of cases was 39.00 ± 13.93 years and mean age of the control group was 40.31 ± 17.40. Most of the patients affected with psoriasis were in the age group of 30-60 years with a male predominance (M:F -1.5:1). 5% of the cases had bizarre morphology with a relatively lower MCD 6.6/mm than in the controls 8.41/mm. 20.0% and 17% of the cases had dilated Capillaries, tortuous capillaries respectively, while 13% and 11% cases showed haemorrhages and avascular areas respectively. Micro vessel density of psoriatic plaques quantified by IHC showed no significant correlation with any of the capillaroscopic findings. Conclusion: Evidences gathered support the role of NVC in the assessment of peripheral microcirculatory changes associated with systemic diseases. They provide a window for the visualisation of dermal capillaries, their morphological alterations and structural abnormalities, along with real time assessment of their functional dynamics.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran