The aim of the study is to assess the level of knowledge and knowledge on practice regarding prevention of covid-19 among B.Sc nursing students OBJECTIVES OF THE STUDY: • To assess the knowledge and knowledge on practice regarding prevention of COVID-19 among B.Sc(N) students • To determine the association between knowledge and knowledge on practice scores regarding prevention of covid-19 with their selected socio demographic variables • To evolve and distribute a self instructional module regarding prevention of COVID-19 infection Methodology: By using Non probability-Purposive Sampling Technique, Non experimental-Descriptive Research Design was adopted, 100 B.Sc nursing students were taken for the study and data was collected by using a self structured questionnaire and analysed by using descriptive and inferential statistics. Results: The results revealed that out of 100 that majority 45(45%) of sample had moderate knowledge rest of 35(35%) of them had adequate knowledge and 20(20%) of the nursing students had inadequate knowledge. Conclusion: Covid-19 is a emerging condition which made the entire world to suffer and bring frontline worriers nurses should take active part in preventing the spread of disease and should promote the awareness among the community in order to implement the researcher has taken this study.