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Tumor associated tissue eosinophilia - a prognostic marker in malignant tumors

Author:

Dr. Rana K. Sherwani, Dr. Nadia Shirazi, Dr. Kafil Akhtar and Dr. Anjum Ara

Subject Area:

Health Sciences

Abstract:

Tumor associated tissue eosinophilia (TATE), is characterized by the presence of eosinophils as a component of peri and intra tumoral inflammatory response. The present study on 92 cases of diagnosed malignant tumors was undertaken to assess the role of tissue eosinophilia as a prognostic factor in malignant tumors; to verify the association between tumor associated tissue eosinophilia, microscopic neoplastic characteristics as well as tumor tissue inflammatory response and to evaluate the role of blood eosinophilia on the prognosis of malignant tumors. The study concluded that tumor associated tissue eosinophilia is associated with absence of metastasis and has a protective role in the spread of squamous cell carcinomas, with a high grade TATE being a favourable prognostic indicator in squamous cell carcinomas.

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