Introduction: The purpose of this study was to evaluate & compare cleaning ability of two different single file rotary files. Methods: 20 canals of 10 extracted molars were selected. After preparing an access cavity, K-file size #15 was introduced into the root canal and India ink was injected. Twenty samples were randomly divided in to experimental groups in group I (n=10), root canals were prepared with OneShape file; in group II (n=10), WaveOne were used for instrumentation. After clearing, the removal of India ink from cervical, middle, and apical thirds was scored. Results: Thus, clening ability in One shape group is better than group Wave one or the Scores for coronal, middle and apical third of root is better in One shape as compared to wave one (i.e. p<0.01) Conclusions: Cleaning efficiency of OneShape system is better than WaveOne system.