Regeneration of immature necrotic tooth using second generation platelet concentrate

Introduction: Regenerative endodontics in immature necrotic teeth helps in root elongation and dentinal wall thickening. This case reports the use of Platelet rich Fibrin as a scaffold for regeneration in such tooth. Methods: An 11year old boy with the history of trauma was diagnosed with the pulpal necrosis, open apex and symptomatic apical periodontitis in tooth #21. Access preparation and minimal instrumentation was done to remove necrotic debris under copious irrigation with 2.5% sodium hypochlorite. Triple antibiotic paste was packed in the canal for four weeks. The intracanal medicament was removed and Platelet rich fibrin (PRF) prepared utilizing Choukroun's method was pushed to the apical region of root canal. Access cavity was sealed with GIC coronally and tooth was permanently restored with composite. Results: Clinical examination at 6 and 12 months revealed no sensitivity to percussion and palpation in tooth #21. Radiographic examination showed resolution of periapical rarefaction, further root development and apical closure of the tooth #21. Conclusion: On the basis of successful outcome of the present case it can be stated that PRF clot may serve as a scaffold for regeneration in necrotic immature teeth.