Use of platelet rich fibrin in post surgical jaw defect

Introduction: Reconstruction of bony defects represents a challenge for the oro-facial reconstruction team. Defects in the facial skeleton present several prosthetic, functional challenges unique to the stomatognathic system. The major aim of the reconstruction is to achieve complete regeneration and restoration of function. However, this becomes a daunting task as the body’s immune and inflammatory mechanisms come into play simultaneously allowing repair to occur; instead of complete regeneration. Recently, the use of platelet concentrates has been proposed as an aid for enhancing regeneration of osseous and epithelial tissues in oral surgery. Aim: To evaluate platelet rich fibrin (PRF) as an autologous grafting material in 3rd molar extraction sockets as post- surgical jaw defect. Materials and methods: A total of 15 patients of either sex, aged between 19-30 years were selected to be a part of this study. They were divided into two groups: group I: Third molar extraction socket with Platelet rich fibrin (PRF) placement after extraction (Test). Group II: Third molar extraction socket without Platelet rich fibrin (PRF) placement after extraction (Control). Post extraction instructions were given and the patients were recalled for follow-up on the 3rd, 7th day post-operatively and also after 1 month, 2 months and 6th month for recording of radiographic parameters. Results: Statistically significant difference with reference to the periodontal pocket depth, distance between CEJ to highest point of alveolar bone and bone density of regenerate was noticed. However, no statistically significant difference between the 2 groups was recorded in pain, extra-oral obvious swelling. Conclusion: platelet rich fibrin (PRF), can be of paramount importance in minimizing periodontal complications that may follow the extraction of impacted lower third molar.