Background: Pre-eclampsia is a common complication of pregnancy constituting major cause of maternal and foetal morbidity and mortality. It develops in 4% - 5% of pregnancies. Altered renal function is an essential component of the patho-physiology of pre-eclampsia, which could lead to acute renal failure. The kidneys play a significant role in the turnover of low molecular weight substances like Urea, Creatinine, Uric acid and Cystatin C. Aims and Objectives: To study serum cystatin C in pre-eclampsia and compare it with serusm Creatinine. To assess whether serum cystatin C is an early and better marker than Creatinine of renal dysfunction in pre-eclampsia. Materials and Methods: A Case - control study comparing 30 pre-eclampticprimigravida inthe third trimester with 30 normotensive primigravida of same gestational age from Vani Vilas Hospital, Bangalore. No history of Hypertension, Diabetes mellitus or Renal disease in cases and controls. Results: Serum Cystatin C was found to be increased in pre-eclamptic patients when compared to controls. Serum Creatinine was within reference range in both cases and controls. Conclusion: Serum Cystatin C is an early and better marker of renal dysfunction in pre-eclampsia compared to serum Creatinine.
- Home
- About us
- EDITORIAL BOARD
- INSTRUCTION TO AUTHOR
- Current Issue
- Archive
- July 2024
- June 2024
- May 2024
- April 2024
- March 2024
- February 2024
- January 2024
- December 2023
- November, 2023
- October 2023
- September 2023
- August 2023
- July 2023
- June 2023
- May 2023
- April 2023
- March 2023
- February 2023
- January 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- February 2022
- January 2022
- December 2021
- November, 2021
- October, 2021
- September, 2021
- August, 2021
- July, 2021
- June, 2021
- May, 2021
- April 2021
- March 2021
- February 2021
- January 2021
- Submit Article
- Certificate
- Reviewers Form
- Contact Us