Ameloblastoma is a locally aggressive, benign odontogenic neoplasm of ectodermal origin comprising of about 1% of the tumors and cysts of the jaws commonly appearing in the third to fifth decades of life. The most common site of occurrence is mandibular molar-ramus region. Despite being a benign entity, the tumor frequently shows local invasion with occasional metastasis. Amelobastoma in young persons are thought to be a rare entity which includes approximately 10-15% of all ameloblastomas. Plexiform amelobastoma with an unusual large size in a 20years old female is presented here, with its clinicopathological, radiological and histological features along with brief review of literature.