Aim: To presume how Alzheimer's and Parkinson's neuropathies may compromise chewing and swallowing mechanisms in individuals with these diseases. Methodology: Used the following main health databases: PUBMED, ScIELO, Google Scholar; There is period from 1959 to 2017. Alzheimer's Disease, Parkinson's Disease, Mastication, Swallowing (Swallowing). We selected 27 articles that fit the following inclusion criteria: Systematic reviews, literature review, clinical case, articles available as variables under study. Results: It has been observed that both Alzheimer's disease and Parkinson's disease has increased considerably in the community due to elevated life expectancy, since it affects the masticatory and swallowing muscles making them as well as compromised, and there is a dysfunction of the system Of cholinergic receptors present in the central nervous system, accumulating proteins and leading to neuronal death. Conclusion: Neurodegenerative diseases are both aggressive and progressive, thus attacking the muscles and causing weakness, as well as impairment of masticatory, motor, behavioral, learning, and other functions.