Abnormal vaginal discharge (AVD) is an initial and one of the commonest clinical problem of women belonging to reproductive age group. It is considered to be the second most common problem after menstrual disorders. Cases of AVD is increasing with time especially in the rural population due to poor hygienic practices, low socio-economic status, structural and social inequalities and lack of awareness about the disease and its various complications. Social stigma and gender discrimination discourage women from revealing their reproductive and sexual health issues which also prevents them from taking medical help at proper time, in proper way. The present study was carried out to determine the sociodemographic and clinicopathological profile of AVD in women of reproductive age group coming to Acharya Vinobha Bhave Rural Hospital, Sawangi (M), Wardha – a rural teaching hospital with tertiary healthcare facilities in vidarbha region and also to critically appraise the therapeutic modules. This monocentric hospital based observational study was carried out between 1st January 2015 to 15th August 2017 in Obstetrics and Gynaecology Department, on 330 women of reproductive age group belonging to rural vidarbha region. Data was collected from in-depth interview of Senior clinicians, Junior residents as well as patients. Out of 330 study subjects, the total no. of AVD cases was 48.15% in 2015; 7.58% in 2016 and 44.24% in 2017. Maximum no. of AVD cases were found to be in females belonging to 36 – 45 years (49.09%) of age group, followed by 26 – 35 years (40.61%) and 15 – 25 years (10.30%). Most common clinicopathological causes of AVD were found to be Bacterial Vaginosis (66.06%), followed by Vaginal Trichomoniasis (24.24%), Mixed infections (06.36%) and Vaginal candidiasis (03.33%). Drugs prescribed to patients were Metronidazole (90.30%), CLID – V Pessary (72.72%), FAS – 3 KIT (06.36%), Fluconazole (03.33%), Candid Pessary (03.33%) and Doxycycline (0.30%). Statistical significance f the study was calculated by using descriptive and inferential statistics using chi square test and p value < 0.05 was considered as level of significance. Software used in analysis was SPSS 17.0 version and GraphPad Prism 6.0 version. Cases of AVD is increasing at an alarming rate in rural vidarbha region and there is no significant change in final outcome of recently prescribed treatment modules. It is recommended that counselling of male and female partners should be carried out through public health awareness camps at a regular interval, especially in the rural region for better hygiene practices, awareness about the disease, prompt consultation in proper way and in order to prevent the various complications of AVD.