Background: COVID-19 has become a great public health concern in the world and has been declared a pandemic. It is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS CoV 2 is a positive-sense single-stranded RNA virus. COVID 19 pandemic has posed a major challenge to the health- care systems across the world. During this acute phase of the pandemic, health care workers have been working day and night to meet the need of the hour and fulfil the requirements of the covid patients and they have been facing various challenges during this pandemic. A study was done to find out the various difficulties faced by nurses anf the possible ways to cope up with the problems. Methods: A descriptive research design was used to identify the challenges faced by Indian nurses by using an electronic web-based questionnaire for data collection by using Google forms, with a consent form appended to it. The questionnaire was available to the participants through social media (Whats App, Facebook and Instagram). Study participants included 100 nursing officers of India working in the hospitals dedicated to the admission and hospitalization of COVID-19 patients. Results: Findings revealed that 42 nursing officers faced severe challenges while caring for covid-19 patients followed by moderate challenges by 34 nursing officers and mild challenges by 24 nursing officers. Conclusion: The study concluded that maximum nursing staff faced severe challenges while serving Covid-19 patients.