Comparative efficacy of ceftriaxone, enrofloxacin and amoxycillin - cloxacillin in subclinical mastitis affected cows

The study was conducted to evaluate the comparative efficacy of ceftriaxone, enrofloxacin and amoxycillin - cloxacillin for therapeutic management of subclinical mastitis affected cows. Ten apparently healthy Jersey crossbreed cows were taken as healthy control group. A total of 30 Jersey crossbred cows with history of reduction in milk yield were subjected to clinical examination, haematology and special examination of milk including bacterial culture and antibiotic sensitivity test. Based on antibiotic sensitivity test subclinical mastitis affected cows were divided into three treatment groups, each comprises 10 cows. The first group was treated with ceftriaxone, while the second and third groups were treated with enrofloxacin and amoxicillin - cloxacillin respectively. Whereas the healthy control group no treatment was advocated. Clinical examination of udder revealed no significant changes following therapy in all the three treatment groups. Haematological study of subclinical mastitis affected cows reveled leukocytosis with neutrophillia and eosinophillia before treatment and after treatment the haematological values reached the normal level. The physical examination of subclinical mastitic milk reveled no changes in colour, consistency and odour. The chemical examination reveled increased pH, electrical conductivity, somatic cell count, chloride content and positive scores of modified whiteside test and modified california mastitis test in subclinical mastitis affected cows before treatment and the values reached normal levels after treatment. The present study has shown better therapeutic efficacy of ceftriaxone compared to enrofloxacin and amoxycillin - cloxacillin in treatment of subclinical mastitis affected cows.