Aim and Objectives: The present study was undertaken to evaluate and compare the remineralization potential of three different dentifrices with different composition (fluoro calcium phosphosilicate, nano-hydroxy apatite, calcium sucrose phosphate) on artificially induced carious lesions in vitro through scanning electron microscopy and quantitative assessment by energy dispersive X-ray spectroscopy. Materials and method: The present in vitro study conducted on 30 caries free impacted third molars with intact surfaces divided into three groups (10 each). Artificial demineralization was carried out, followed by remineralization using dentifrice slurry as per the group allocation. After 10 days period the entire test groups were evaluated with HRSEM and quantitative assessment by energy dispersive X-ray spectroscopy .the obtained data was analyzed statistically using one way ANOVA, student’s t test and tukey’s multiple comparison tests.p≤ 0.05 was considered to be significant. Results: All three dentifrices tested showed remineralization although insignificantly different from each other but highlights the concept of biomimetic bioactive glass as an effective remineralizing agent. Conclusion: To focus on the importance of minimal invasive treatment on incipient carious lesion by remineralization.
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