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Consensus statement on the use of high-sensitivity troponin i assay for risk stratification of apparently healthy individuals – an Indian dimension

Author:

Abraham Oomman, Jamshed Dalal, C.K. Ponde, Manish Bansal, J.P. Sawhney, Brian Pinto, Neeraj Bhalla, Sanjeev Gera, Peeyush Jain, Rishi Gupta, Bharat Shivdasani, Kiron Varghese, Akshay Mehta, Sadanand Raghunath Shetty, Subhash ChandManchanda, Nikhil Parchu

Subject Area:

Health Sciences

Abstract:

The burden of cardiovascular (CV) diseases in India highlights the need for early prevention and limitations of current practices. Evidences support the use of high-sensitivity troponin I (hsTnI) as a potential stratification tool for identifying at-risk individuals. The currently available hsTnI assay sallow the detection of low circulating cardiac troponin concentrations, thus making ita potential predictor of risk in even asymptomatic individuals. Based on these reports and the availability of a CE-approved, cardiac-specific, ARCHITECT hsTnI, for CV risk stratification in apparently healthy individuals, an expert panel of cardiologists across India was convened. The panel discussed and arrived at a consensus on the feasibility of hsTnI assay in CV risk stratification of apparently healthy individuals in Indian settings and also proposed an algorithm. This consensus statement acts as a pragmatic guide for clinicians on the use of hsTnI assay as a prognostic marker and a guide for planning prevention strategies.

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