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Diagnose and treatment of hypopharyngeal cancer with primary cancer of upper digestive tract at same time

Author: 
Hassan Osman Mohamed, Weng Ming Li, Menghan Gao and Da Peng Lei
Subject Area: 
Health Sciences
Abstract: 

To analyze the characteristics and diagnosis of hypopharyngeal and esophageal double primary cancer and explore the treatment strategy of hypopharyngeal and esophageal (1,2) double primary cancer. We collected and analyzed n= 49 patients with hypopharyngeal and esophageal double primary cancer. The total number of patients was 49. There are male and female patients. N=47 male, N=2, female, and they are all diagnosed with hypopharyngeal esophageal double primary Synchronous cancer. 18 are younger than age <55, 18 were about 55-65, 13 were over age> 65. The clinical data of patients with hypopharyngeal and esophageal double primary cancer from February 2017 to September 2019, these patients came to our department of Otorhinolaryngology in qilu hospital of Shandong university .for the first time because of pharyngeal disease, after we find hypopharyngeal cancer, esophageal cancer found by performing a gastroscopy, we collected to date of patients (n=49), in Qilu hospital were retrospectively analyzed data, Including the auxiliary examination method, gastroscopy examination all patient showed no symptoms of esophageal discomfort, among 17 cases were evaluated for hypopharyngeal tumor who could not preserve laryngeal function total laryngectomy total esophagus, resection, and total tubular gastric replacement, was performed, in all 17 cases. There were 5 cases of hypopharyngeal and esophageal resection with preserving laryngeal cancer were used. There a clinical-stage of esophageal cancer was used minimally invasive surgery under gastroscopy. There were 8 cases of hypopharyngeal carcinoma resection with laryngeal function preservation and gastroscopic esophageal lesion. Endoscopic submucosal dissection,ESD was used. The remaining 19 cases were treated with radiotherapy. Due to physical tolerance, there was not perform a surgical operation. There were 5 cases of death due to postoperative complications of the liver and lung metastasis. for the long term treatment and the follow up was about 37 months, there is a classification of pathological and the survival.

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