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Difficult preoperative diagnosis of multifocal pancreatic intraepithelial neoplasia arising from long-standing benign cystic lesions: a case report

Author:

Mirac Gunay, MS and Jamshed Zuberi, MD

Subject Area:

Health Sciences

Abstract:

Pancreatic intraepithelial neoplasia is a premalignant tumor that arises from ductal epithelial cells of the pancreas. It is generally less than 5mm in size and affects individuals older than age of 50 years. Diagnostic studies used to visualize pancreatic cancers include computed tomography scan, magnetic resonant imaging, and abdominal ultrasound. Pancreatic intraepithelial neoplasia is not well visualized in these diagnostic imaging studies and thus it is difficult to diagnose without intraoperative tissue sampling. We present a case of multifocal pancreatic intraepithelial neoplasia originating from benign cystic lesions in the body and tail of pancreas, which was discovered postoperatively only, despite all the imaging modalities.

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