Objectives: To compare the effect of subscapularis soft tissue mobilization and proprioceptive neuromuscular facilitation on glenohumeral external rotation in periarthritis shoulder. Design: Comparitive study of quasi experimental design Settings: The study was conducted in SRM Medical Hospital& Research Center, Kattankulathur. Procedure: Subjects diagnosed with periarthritis shoulder are divided into two groups, the treatment for one group was given with subscapular soft tissue mobilization and other with proprioceptive neuromuscular facilitation on glenohumeral external rotation. Results: There was significant difference in subscapular soft tissue mobilization and proprioceptive neuromuscular facilitation on glenohumeral external rotation on periarthritis shoulder between the groups P<0.000. Conclusion: The study concluded that there was a significant reduction of pain and improvement of glenohumeral external rotation range of motion of both groups.