Aggressive periodontitis renders a great challenge to the conventional implant due to the risks of infection and ongoing marginal bone loss (MBL).The “All-on-Four” concept is based on the placement off our implants (two axial and two tilted implants) in the anterior part of fully edentulous jaws to support a provisional, fixed, and immediately loaded full-arch prosthesis. Little is available about this treatment modality in patient with aggressive periodontitis. The following case report describes a case of Full Mouth Rehabilitation using All on 4 Implant concept in a female patient with Generalised Aggressive Periodontitis followed up for 4 years.