Inflammatory myofibroblastic tumour: Case series of 12 patients in rural hospital of central India

Background: Inflammatory myofibroblastic tumour is rare and benign type of soft tissue neoplasm. It is proliferative type of lesion which mimics like a malignancy due to its unknown etiology clinically, radiographically and histopathologically. It consists of myofibroblastic proliferation along with various types of inflammatory infiltrates. The diagnosis is made based on clinical, radiological, histopathological and Immunohistochemistry (IHC) findings which differentiate it from other soft tissue tumours. Excision method is used in all patient as treatment part.Objective: To characterize the clinical presentation, radiological presentation, diagnosis by histopathology and IHC for the treatment of inflammatory myofibroblastic tumour. Materials and methods: This is an observational retrospective study based on a case series. Data was collected after reviewing the medical records of patients from HIS diagnosed with inflammatory myofibroblastic tumour at our rural hospital in Sewagram between January 2010 and July 2023. The data included age, sex, symptoms, location, size, USG/CT, Histopathology /IHC, surgical approach and follow up. Results: There were 12 patients diagnosed with inflammatory myofibroblastic tumour. Their mean age was 47.5 years, out of 12 patients, 09 were women and 03 were men. Conclusions: Inflammatory myofibroblastic tumour is very challenging for establishing the diagnosis due to its varied clinical, radiological and histopathological presentation. IMT can confuse with malignant tumours. Diagnosis depends on their histopathological and IHC findings of patient while treatment part on the size and location of tumour. Treatment options vary patient to patient, ranging from surgical resection from minimum endoscopy procedure to open surgery.