Laparoscopic splenectomy for isolated sarcoidosis of spleen

Sarcoidosis is an inflammatory disease with an unknown etiology. The main manifestation of sarcoidosis is due to involvement of the pulmonary system, in which it presents as a noncaseating granulomas and generalized lymphadenopathy. It is generally a multisystem disease that presents with a wide spectrum of differential diagnosis including infectious,autoimmune,neoplastic conditions of spleen. However, isolated granulomatous disease confined to spleen is rare. The approach to isolated splenic nodules in a patient with nonspecific abdominal symptoms should be focused on exclusion of malignancies and infections, and may require computed tomography, magnetic resonance imaging, and positron emission tomography–computed tomography imaging; scintigraphy; bone marrow biopsy; breast and genital examinations; and endoscopies. We report a rare case of isolated sarcoidosis of spleen which was treated laparoscopic ally.