CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Morphological alterations in the podocytes following chronic simultaneous administration of ethanol and acetaminophen in kidneys of adult wistar rats (rattus norvegicus)

Author: 
Fakunle P.B., Ajibade A.J., Ehighie L.O., Oyewo O.O. and Adeleke F.O
Subject Area: 
Life Sciences
Abstract: 

Aims: Ethanol and acetaminophen have been separately reported with various effects on the functionality of the kidney but information on the level of impact when simultaneously administered chronically is scanty hence effects of chronic simultaneous administration of ethanol and acetaminophen were investigated. Place and duration of study: This research work was carried out in the Anatomy department of Ladoke Akintola University of Technology,Ogbomoso,Nigeria between 2010 and July 2011. Methodology: Forty adult wistar rats of average weight 200±3.21g, randomly distributed into 4 groups A,B, C and D (n=10 ).The animals were fed with standard mouse chow with water provided ad libitum. Animals in group A were given100mg/Kg.bwt. acetaminophen and 25% ethanol in 2% sucrose solution while group B animals were given 100mg/Kg.bwt. The group C animals received 25% ethanol in 2% sucrose solution and lastly the animals in group D were given only distilled water all for a period of 6 weeks. At the end of administration the animals were sacrificed by cervical dislocation and the wet weight of each kidney specimen was documented. The kidney specimens were fixed in 10% formol saline and then processed for routine histological techniques, sectioned at 6µ and stained with H&E. Results: Significant body weight loss P<0.05 was observed in the treatment groups A and B compared to the control. Distortion of the podocytes as well as pyramidal cells in the proximal and distal convoluted tubules were observed in all the treatment groups although more marked in group A than in group B compared to the normal cells in the controls. Conclusion: This may underline impaired filteration and tubular fluid reabsorbtion properties of the kidney.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran