CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

A prospective comparative study evaluating the impact of hemi body irradiation VS focal RT plus zoledronate in management of painful skeletal metastases

Author: 
Bidyut Mandal, Abhishek Basu, Anish Bandyopadhyay, Avik Maji, Pratyusha Mukherjee and Prof. S. K. Sikdar
Subject Area: 
Health Sciences
Abstract: 

Objectives: The primary objective of our study is to evaluate the effect of Hemi Body Irradiation and Focal Radiotherapy with Zoledronate on pain management in patients with extensive bone metastases after completion of definitive treatment. The secondary objective is to evaluate the toxicities and Skeletal Related Events eg. fracture. Material and Methods: We have analyzed the difference in pain reduction comparing two groups of patients in a prospective non randomised study . The first group comprised of 10 patients treated with Hemibody Irradiation (HBI), the second one included 14 patients treated with focal radiotherapy and zoledronic acid, 4mg iv, 4 weekly (RT + ZA). In both groups single fraction radiation of 8Gy (UHBI = 6Gy) was given & followed up for 3 months .All patients were assessed before, during and after treatment with a questionnaire that rated the grade of pain, type of analgesic therapy and patient’s performance status. Response assessment was done using Visual analogue scale, percentage of pain relief and total score reduction on a scale of 0 - 20. Acute & chronic haematological and GI toxicities were assessed as per standard guidelines. Statistical analysis was done by Chi square test & Mann-Whitney U test. Results: Long term pain score & total score reduction was more in (RT + ZA) arm (P =0.002 & 0.001) with less toxicity (P=0.002) and SRE.(P=0.324) Conclusions Focal RT with ZA showed better result on long term pain management and may be preferred in cancer patients with longer median survival. As our sample size was small, study with larger sample size is warranted.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran