The concept of “food addiction” has received increasing attention in recent clinical and experimental investigations (1,3). While cogent arguments have been made against the establishment of food addiction as a psychiatric diagnosis in its own right, there is a substantial evidence to suggest a significant role in the process of substance abuse disorders(4). Proposed review research has inherent limitations based on the scarcity of data on food addiction derived from clinical trials, which seriously limits the possibility of treatment recommendations (5). Diagnostic criteria for “food addiction” are controversial, and the heterogeneity of the studied population also limits the possibility of formulating screening strategies that are already implemented for other addictive disorders (11). Food addiction could possess strong implications on various aspects of life (12). Food addiction, if left ignored or untreated it can rapidly alter the biomechanics and health quality of an individual (5). Furthermore, validating data base relative to the concepts of toxic and lethal doses of hyper palatable foods on humans are crucial, as doses below the toxic and/or lethal range perhaps play a causal role in inducing intoxication or death. Evidently formulating a cohesive approach to diagnosis and treatment uniquely enable a vital impact on the proliferation of food addiction in the coming years.