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Relapsing polychondritis with c-anca positivity without clinical vasculitis
Subject Area:
Health Sciences
Abstract:
Relapsing polychondritis is a rare chronic inflammatory disorder primarily involving the cartilaginous structures of ears, nose and tracheobronchial tree. The disease can involve the eyes and the muskeloskeltal system with seronegative non erosive arthritis. We described a case of a 25 year female with relapsing polychondritis. This patient presented with history of throat pain, difficulty in breathing, hoarseness of voice from last one week and bilateral hearing impairment. On examination patient had bilateral auricular involvement with sparing of ear lobules, conjunctivitis, nasal chondritis and subglotic edema. Investigations revealed c-ANCA positivity and bilateral sensori-neural hearing loss. Patient was started on steroid therapy immediately and her symptoms improved.
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