This review focus on several emergency drugs which should be always present in the pediatric dental office for the treatment of medical emergencies or to prevent their occurrence in dental clinic. Drugs used for adults can be inadequate for treatment of medical emergencies in a pediatric dental patient. So emergency drugs should be individually prepared for use or they can be commercially available as emergency drug kit. This drug kit should contain all emergency drugs with recommended dose for use by the pedodontist according to the needs of emergency and training of the dental practitioner.