Verrucous carcinoma (VC) was first described as a distinct clinico-pathological entity by Ackerman in 1948. The name of this variety of Squamous cell carcinoma makes it distinctive. Although this carcinoma has been reported in extra-oral sites, it is a rare intra-oral entity, commonly found in oral mucosal sites. The common sites of occurrence of VC are buccal mucosa> gingiva> alveolar ridge> palate and floor of mouth and very rarely on tongue. Here we report a rare case of a large Verrucous carcinomatous lesion on left lateral anterior region of tongue in 78 year old female associated with human papilloma virus 16 without any history of tobacco related habits.