Health related quality of life screening with medical outcomes study 12-item short-form health survey (mos sf 12) and 14-item short-form health survey for chronic venous insufficiency (mos civiq 14) thai versions

Background: Chronic venous disease (CVD) was a high incidence meanwhile patients did not seek treatment at early stage. Relevance leg symptoms spotted for primary screening remains clinical challenges. Method: The medical outcomes study (MOS) with health-related quality of life, a12-Item Short-Form Health Survey (MOS SF12) and a 14-Item Health Short-Form Health Survey for Chronic Venous Insufficiency (MOS CIVIQ14) were employed in hospital-setting together with physical examinations for an interventional study.A cross-sectional analysis was performed to assess reliability and correlation of the questionnaires with specific implication of leg symptoms. Result: Overall 120 patients were screened, out of this 48 patients clinically diagnosed CVD. For inter-scale correlation and internal consistency reliability interpreting with Cronbach’s alpha coefficients, the MOS CIVIQ-14 Thai version were reliable with Cronbach’s alpha coefficient of 0.914(for 14-item global score), 0.867(for 7-item physical and pain score) and 0.787(for 7-item psychological score), whereas the MOS SF-12 were reliable with the above 0.810(for 12-item for global score), 0.939(for 7-item physical and pain score) and 0.661(for 5-item mental score). The two questionnaires were well correlated for physical score, interpreting with bivariate Pearson correlation coefficient, with a 95% CI of 0.713(0.663 to 0.790), p<0.001 and for global score, 0.745 (0.640 to 0.819), p<0.001). No significant correlation of psychological score of -0.062(-0.197 to 0.091), p=0.501. The major leg symptoms significantly have rendered impacts on the raw score of physical components and global score but not for mental component. Patients with MOS CIVIQ-14 score lower than 75.7 would be more likely to have been diagnosed CVD. Conclusion: Both the MOS CIVIQ-14 and the MOS SF 12 were highly correlate for scoring on physical function, useful for primary screening of chronic venous disease. Should the procedures be use in a larger population, the majority of leg symptoms and adjustment of appropriate threshold scores may be a useful tool for screening CVD. The MOS CIVIQ-14 was useful but larger heterogeneous patient exploration confirmation is suggested.