Antimicrobial activity of crude ethyl acetate extract of marine actinomycetes isolated from marine sediments

Actinomycetes are wide spread in nature and known for production of bioactive metabolites. Marine source world-wide are considered to be rich for bio-resource and efforts has been taken to identify new bacterial agents from marine environment for human welfare. In this study, we reported isolation of 20 Actinomycetes strains from marine sediments and tested with standard biochemical test and utilization of carbon sugar, to confirm the Actinomycetes character. Among the isolates 17 and 3 were recorded to be gram positive and gram negative respectively. Carbon utilization test revealed that all the isolates utilized dextrose and none of the isolates utilized ducitol. Antagonistic activity of 20 strains revealed that six strains (PS2, PS4, PS9, PS11, PS13 and PS14) are positive and crude ethyl acetate extracts of strains PS4, PS11, and PS14 were showed good antimicrobial activity. The isolate PS14 dominant over other isolates and revealed promising antimicrobial activity.