In vitro anti-inflammatory activity of different varieties of Musa sapientum (Banana) peel extract

In the present study, the 50% hydro ethanolic extract of different varieties of Musa sapientum (Musa spp.) peel such as Nendran (Musa spp. - French Plantain - AAB), Pachanadan (Musa spp. - Pachanadan - AABS), Rasthali (Musa spp. - Rasthali – AAB and Sevvazhai (Musa spp. - Red banana - AAA) was evaluated for in vitro anti-inflammatory activity. Inhibition of protein denaturation, RBC membrane stabilization and proteinase inhibitory activity was assessed at a concentration of 0.1g/ml for all the varieties. The standards used in this study include aspirin and diclofenac sodium. Of the four varieties used in the present study, Rasthali was found to have maximum inhibiting effect on albumin denaturation (63.42%) and RBC membrane stabilization (53.94% and 46.18%). Proteinase activity was also maximally inhibited by Rasthali (71.78%) when compared to others. From the results it can be concluded that Rasthali peel extract exhibited significant anti inflammatory activity when compared to other varieties and it may be due to phytoconstituents in it.