Marjan (Corallium rubrum) belongs to phylum Cnidarians & family Coralliidae. Marjanis animal origin drug, its two types ‘Beekh-e-Marjan’ or ‘Busud’ (Root of coral) and Shakh-e-Marjan (Branch of coral), Marjan contains around 85% of the wet weight of calcium carbonate in the form of calcite and 5% other elements such as Mg, Fe, SO4, P2O5, SiO2, Pb, Zn, and an organic matrix. Its therapeutic uses in astringent, styptic, antidiarrheal, diuretic, antiseptic, detoxificant and tonic for the heart and brain, it is useful in melancholia, epilepsy, insanity, palpitation, enlargement of spleen, gastric disorder renal calculi and piles. Administration with egg yolk gum acacia and catechu is recommended in stomatitis, haemoptysis, cough, phthisis and asthma. Its use has also been mentioned in impotence, spermatorrhoea, gleet, gonorrhea, carbuncles, scrofulous affections, tuberculosis, diabetes, and general debilities. Pharmacological study of Marjan (Corallium rubrum) likes, Antibacterial activity, Anti-osteoporotic activity, Anti-atherosclerotic activity, Haemostatic activity, Hepato-protective activity, Anti-hyperacidity activity